Articles Population Study nature publishing group Background: Intrapartum hypoxic events (“birth asphyxia”)

may result in stillbirth, neonatal or postneonatal mortality, and impairment. Systematic morbidity estimates for the bur-den of impairment outcomes are currently limited. Neonatal encephalopathy (NE) following an intrapartum hypoxic event is a strong predictor of long-term impairment. Methods: Linear regression modeling was conducted on data identified through systematic reviews to estimate NE inci-dence and time trends for 184 countries. Meta-analyses were undertaken to estimate the risk of NE by sex of the newborn, neonatal case fatality rate, and impairment risk. A compart-mental model estimated postneonatal survivors of NE, depend-ing on access to care, and then the proportion of survivors with impairment. Separate modeling for the Global Burden of Disease 2010 (GBD2010) study estimated disability adjusted life years (DALYs), years of life with disability (YLDs), and years of lif